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- On April 21, at least 20 civilians were injured in the IDF attack on Al-Aqsa Mosque and the suppression of Palestinian worshipers, according to the Palestinian Red Crescent;
- On April 21, Israeli warplanes attacked the al-Qassam Brigades base in the center of Gaza;
- On April 21, Israeli artillery attacked areas east of Khani Yunis;
- On April 21, clashes between Israelis and Palestinians continued in the Al-Aqsa Mosque;
- On April 20, Palestinian groups fired several rockets at the Sderot region.
